his
text by John McMurry and Tadhg Begley on The Organic Chemistry of
Biological Pathways provides a contemporary and authoritative treatment
of the molecular logic of the chemistry of life...The authors have chosen
to organize the text not by organic reaction type but by metabolic pathway.
Doing so allows them to explain not only the chemistry of any given
step but also the molecular logic of the entire pathway. Readers thus
gain a deeper understanding of how and why the organic molecules of
life undergo their sequential transformations and interconversions.
To integrate the information from earlier chapters, as well as tie in
traditional modes of organic reaction classification, the authors conclude
with a summary chapter of the most common reaction types encountered
in metabolism.
--- from the Foreword by Christopher T. Walsh, Harvard University
Book Review, Chemistry & Biology, Feb. 2005
"The book's greatest strength is its emphasis on the conceptual unity of organic chemistry and biochemistry. The chemical structures are presented with great care and accompanied by lucid explanations."
---Charles Clapp, Bucknell University
"This textbook elegantly portrays the complementary nature of chemistry and biology. By describing biological processes in detailed chemical terms, the authors have provided a resource that provides an unparalleled look into the fascinating and emerging field of chemical biology."
--Hung-wen Liu, University of Texas
"This textbook satisfies a major need in chemistry curricula, bridging the gap between introductory organic chemistry and biochemistry/biology. It is the first book written for students that presents biological transformations from the perspective of organic mechanism. The book significantly augments modern biochemistry curricula and may catalyze a resurgence of interest in biological mechanism."
---Carolyn R. Bertozzi, University of California, Berkeley
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